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Learning pain. Recent learnings from experimental, clinical and implementation studies

How we learn pain, and learn about it, is a rapidly changing field. In this talk I will present a snapshot of recent research by our group and collaborators on how our pain system learns and thus increases or decreases protection. I will discuss the current evidence for and against associative learning of hyperalgesia and allodynia and that, within the context of predictive processing, findings that may explain some of the hitherto problematic aspects of persistent pain and recovery. I will draw on clinical studies that cast significant doubt over common presumptions concerning ‘central sensitisation pain’ and the clinical and theoretical justification of categorising pain states into one of three boxes. I will present new data that highlight our failings in teaching people about pain, the opportunities that are arising to do it better. Finally, I will present new implementation strategies and a novel approach to embedding clinicians-as-scientists as a strategy to overcome an increasing divide between clinician’s experience of treating patients and scientist’s advice about how to do it.

Lorimer Moseley

  • Qualifications: BAppSc(Phty)(Hons) (1992) | PhD (2002) | FACP (2011) | DSc (2017) | FAAHMS | HonFFPM(ANZCA) | HonMAPA
  • Previous: NHMRC Post-doctoral fellowship at Queensland University & Sydney University (2002-5)   |  Nuffield Medical Research Fellow, the University of Oxford, UK  (2005-8) | University Fellow, University of Oxford (2009).
  • Current: NHMRC PRF | Professor of Clinical Neurosciences & Foundation Chair in Physiotherapy, University of South Australia | Senior PRF, Neuroscience Research Australia | Chair, Pain Adelaide Stakeholders’ Consortium.
  • Moseley has authored 340 articles. He has given 70 Plenary lectures at major international meetings in 26 countries. Ande he has supervised 25 PhD and 16 Honours students to completion.
  • In the last 5 years he has authored 168 papers and he has given 34 Plenary lectures at major international meetings in 26 countries, including the Biennial World, American, Pan-African and Canadian Pain Congresses.
  • He has won awards or prizes from national pain societies or physiotherapy associations in 12 countries, including the American Physical Therapy Association’s Friend of the Association Award.
  • He is Chief Editor of Body in Mind.
  • He has served on the Scientific Programme Committee and Refresher Course committee of the World Pain Congress. He is on the IASP Steering Committee to establish core outcomes for CRPS research.
  • He mentors 6 post-doctoral, 3 mid-career fellows, a senior research scientist, 8 PhD students. In the last five years, researchers under his mentorship/supervision have won the most prestigious student or trainee awards available internationally from the International Association for the Study of Pain. He won the inaugural Supervisor of the Year Award.
  • In 2018 he reviewed 42 papers.

Lorimer Moseley

  • Qualifications: BAppSc(Phty)(Hons) (1992) | PhD (2002) | FACP (2011) | DSc (2017) | FAAHMS | HonFFPM(ANZCA) | HonMAPA
  • Previous: NHMRC Post-doctoral fellowship at Queensland University & Sydney University (2002-5)   |  Nuffield Medical Research Fellow, the University of Oxford, UK  (2005-8) | University Fellow, University of Oxford (2009).
  • Current: NHMRC PRF | Professor of Clinical Neurosciences & Foundation Chair in Physiotherapy, University of South Australia | Senior PRF, Neuroscience Research Australia | Chair, Pain Adelaide Stakeholders’ Consortium.
  • Moseley has authored 340 articles. He has given 70 Plenary lectures at major international meetings in 26 countries. Ande he has supervised 25 PhD and 16 Honours students to completion.
  • In the last 5 years he has authored 168 papers and he has given 34 Plenary lectures at major international meetings in 26 countries, including the Biennial World, American, Pan-African and Canadian Pain Congresses.
  • He has won awards or prizes from national pain societies or physiotherapy associations in 12 countries, including the American Physical Therapy Association’s Friend of the Association Award.
  • He is Chief Editor of Body in Mind.
  • He has served on the Scientific Programme Committee and Refresher Course committee of the World Pain Congress. He is on the IASP Steering Committee to establish core outcomes for CRPS research.
  • He mentors 6 post-doctoral, 3 mid-career fellows, a senior research scientist, 8 PhD students. In the last five years, researchers under his mentorship/supervision have won the most prestigious student or trainee awards available internationally from the International Association for the Study of Pain. He won the inaugural Supervisor of the Year Award.
  • In 2018 he reviewed 42 papers.

Learning pain. Recent learnings from experimental, clinical and implementation studies

How we learn pain, and learn about it, is a rapidly changing field. In this talk I will present a snapshot of recent research by our group and collaborators on how our pain system learns and thus increases or decreases protection. I will discuss the current evidence for and against associative learning of hyperalgesia and allodynia and that, within the context of predictive processing, findings that may explain some of the hitherto problematic aspects of persistent pain and recovery. I will draw on clinical studies that cast significant doubt over common presumptions concerning ‘central sensitisation pain’ and the clinical and theoretical justification of categorising pain states into one of three boxes. I will present new data that highlight our failings in teaching people about pain, the opportunities that are arising to do it better. Finally, I will present new implementation strategies and a novel approach to embedding clinicians-as-scientists as a strategy to overcome an increasing divide between clinician’s experience of treating patients and scientist’s advice about how to do it.